摘要
良性前列腺增生(BPH)是老年男性常见疾病,目前主要依靠外科手术来治疗,虽然效果较好,但仍给病人带来不同程度的损害,如尿失禁,阳瘘,逆向射精等不良影响.药物治疗也仅适于轻度至中度的病人,且效果不够满意[1].所以寻求新的有效的治疗良性前列腺增生的方法仍是目前和今后研究的热点问题.
出处
《现代泌尿外科杂志》
CAS
2001年第4期60-62,共3页
Journal of Modern Urology
参考文献20
-
1Roehborn CG. Treatment outcomes in BPH. Textbook of Benign prostatic Hyperplasia. Edited by Roger Kirby, Mc Connel, et al. ISAS Medical Media. Ltd. 1996,473 - 501.
-
2Funa K,Nordgren H,Nilsson,et al. In situ expression ofmRNA for protoonceogenes in benign prostatic hyperplasia and in prostatic carcinoma.Scand J Urol Nephrol, 1991 ;25(2) :95 - 100.
-
3Mulligan RC. The bssic science of gene therapy. Science, 1993,260:926.
-
4Bert Vogeston B. Adeadly inheritance. Nature,1990,348:681-687.
-
5Evan G, Littlewood T. Amatter of life and cell death. Science,1998,281(5381) :1317 - 1322.
-
6Schkechte H, Lenk SV, Loning T, et al. p53 tumour suppressor gene mutations in benign prostatic hyperplasia and prostate cancer. Eur Urol, 1998,34(5)433 - 440.
-
7Meryers FJ, Chi SG, Fishman JR, et al. p53 mutations in benign prostatic hyperplasia. J Natl Cancer Inst, 1993,85 (22): 1856 - 1858.
-
8Shiakawa T, Gotoh A, Gaarener TA, et al. P53 adenoviral vector(Ad- CMV- p53)induced prostatic growth inhibition of primary cultures of human prostate and an experimental rat model. J Gene Med ,2000,2(6) :426 - 432.
-
9Baltaic S,Orhan D,Ozer G,et al. Bcl - 2 proto - oncogene expression in low- and high grade prostatic intraepithelial neoplasia. BJU Int,2000,85(1) :155 - 159.
-
10Watanbe M, Nakada T, Yuta H, et al. Analysos of protooncogene c - erbB - 2 in benign and malignant human prostate. Int Urol Nephrol,1999,31(1) :61 - 73.
同被引文献9
-
1邓春华,臧志军,孙祥宙,黄晓卉,王浩,王东,苏胜华.Caspase-1在良性前列腺增生组织中的表达及意义[J].中华男科学杂志,2005,11(11):810-812. 被引量：2
-
2B. Coleman,J.B. Fallon,L.N. Pettingill,M.G. de Silva,R.K. Shepherd.Auditory hair cell explant co-cultures promote the differentiation of stem cells into bipolar neurons[J]. Experimental Cell Research . 2006 (2)
-
3J HSohn,D HKim,N GChoi,Y EPark,J YRo.Caspase‐3/CPP32 immunoreactivity and its correlation with frequency of apoptotic bodies in human prostatic carcinomas and benign nodular hyperplasias[J]. Histopathology . 2002 (6)
-
4Pothana Saikumar,Zheng Dong,Valery Mikhailov,Michael Denton,Joel M Weinberg,Manjeri A Venkatachalam.Apoptosis: definition, mechanisms, and relevance to disease[J]. The American Journal of Medicine . 1999 (5)
-
5Atsushi Suzuki,Masaru Iwasaki,Nobuhiko Wagai.Involvement of Cytoplasmic Serine Proteinase and CPP32 Subfamily in the Molecular Machinery of Caspase 3 Activation during Fas-Mediated Apoptosis[J]. Experimental Cell Research . 1997 (1)
-
6胡建新,何坚,孙兆林.Caspase-3、Bcl-2及bFGF与良性前列腺增生关系的研究进展[J].贵州医药,2007,31(11):1038-1040. 被引量：3
-
7张更,王禾,张波,于翠娟,武国军,秦卫军,孟艳玲,王成济,杨安钢.前列腺特异性抗原启动子调控促凋亡基因caspase-7载体的构建及其对前列腺癌细胞的特异性杀伤作用[J].第四军医大学学报,2003,24(8):711-714. 被引量：1
-
8邓春华,丘少鹏,陈辉熔,郑克立,梅骅,刘建中.Caspase-3在前列腺组织中的表达和意义[J].中国男科学杂志,2003,17(4):224-228. 被引量：14
-
9高建芝,张建龙,王红梅,马琪,腾清蕾.脓毒症大鼠Fas-L、Caspase-3和NF-κB的表达与肝细胞凋亡的关系[J].新乡医学院学报,2004,21(2):96-99. 被引量：11
-
1白丽荣.基因治疗[J].生物学教学,2001,26(11):1-1.
-
2魏玉玲,傅刚,梁克玉.骨修复的新途径——基因疗法[J].中医正骨,2002,14(9):53-54. 被引量：2
-
3李兵仓,廖维宏.基因转移技术在中枢神经系统损伤治疗中的应用及前景[J].国外医学（神经病学．神经外科学分册）,1994,21(5):233-237. 被引量：2
-
4韩一生,金格勒,戴先文,李松建,彭玮丹.基因转移技术在骨关节病研究中的应用[J].中华骨科杂志,1999,19(4):243-246. 被引量：3
-
5刘志红,黎磊石.基因转移技术和基因治疗在肾脏病研究中的应用[J].中华肾脏病杂志,1997,13(1):53-56. 被引量：7
-
6张延龄.基因转移[J].国外医学（创伤与外科基本问题分册）,1996,17(1):1-3.
-
7黄光红.基因治疗的基础科学[J].世界科学,1994,16(5):14-15.
-
8陈小平,宋建良.基因转移技术在整形外科学研究中的应用[J].中华整形外科杂志,2002,18(2):107-107.
-
9李兵仓,廖维宏.基因转移技术在中枢神经系统损伤治疗中的应用及前景[J].战伤参考资料,1994(1):1-7. 被引量：1
-
10黎婉玲.基因新疗法——反基因技术[J].广州医药,1997,28(3):8-9.
