69例新生儿呼吸机相关性肺炎病原菌检测及分析

Pathogenic bacteria detection and drug sensitivity analysis in 69 newborns with ventilator-associated pneumonia

目的: 探讨新生儿呼吸机相关性肺炎(VAP)病原菌耐药情况及防治措施。方法: 对69 例VAP 患儿的临床资料进行回顾性分析。结果: 69例VAP患儿中,死亡5 例,放弃治疗5 例。大肠埃希氏菌、阴沟肠杆菌、肺炎克雷伯杆菌是VAP 3种主要致病菌,耐药率高,对泰能、环丙沙星最为敏感。结论: 革兰氏阴性杆菌是新生儿VAP主要致病菌,耐药率高,应积极预防。

Objective: To detect the pathogenic bacteria sensitivity and treatment in newborns with ventilator associated pneumonia. Methods: An analyse of clinical data of 69 newborns with ventilator associated pneumonia was done. Results: Among the 69 cases of ventilator associated pneumonia, 5 cases was died, 5 cases refused further treatment, mortality rate is 7.25%. Enterobacter cloacae, Escherichia coli and klebsiella pneumonia were the most common bacteria. They were highly tolerant to many antibiotics, but sensitive to tienam and ciprofloxacin. Conclusion: Gram negative bacteria are the most important bacteria in the newborns with ventilator associated pneumonia and has high drug tolerance, It should be prevented and treated carefully.