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产金属硫蛋白酿酒酵母诱变菌株的生物学功能研究

Biological Function of Metallothionein Producing Saccharomyces cerevisiae Mutant
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摘要 以酿酒酵母 (Saccharomycescerevisiae)单倍体菌株SY1为出发菌株 ,通过紫外线和亚硝基胍复合诱变 ,获得 1株Cu2 + 高抗性突变株 ,并对其生物学功能进行了研究。结果表明 ,其拮抗紫外线 ,拮抗电离辐射 ,清除·OH自由基能力 ,Cu2 + 解毒能力均比出发菌株有所提高 ,经 5 0世代培养后 ,其遗传稳定性保持在 96 %以上。 A high Cu{2\} resistant Saccharomyces cerevisiae (SC) mutant was obtained by composite mutation with UV and NTG and SC monoploid as starting strain. Later its biological function was studied. The results showed that its resistance against UV and ionizing radiation, OH free radical clearing, and detoxification against Cu{2\} were higher to some extent than the starting strain, and its genetic stability was maintained over 96%.
出处 《微生物学杂志》 CAS CSCD 2005年第1期36-39,共4页 Journal of Microbiology
基金 山东省教委资助项目 (3 2 174)
关键词 酿酒酵母 金属硫蛋白 诱变菌株 生物学功能 Saccharomyces cerevisiae metallothionein mutant biological functioni
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参考文献6

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