原发性高血压患者空腹胰岛素与血脂测定分析

Analysis of Fasting Insulin and Lipidemia in Essential Hypertension

我们对空腹血糖正常的４１例原发性高血压、３６例高脂血症及３７例正常人，同步测定空腹血糖、血胰岛素及血脂。结果：高血压组空腹胰岛素水平明显高于高脂血症组及正常组（Ｐ＜０．０１）；胆固醇、低密度脂蛋白、甘油三酯也高于正常组（Ｐ＜０．０５）；高密度脂蛋白低于高脂血症组（Ｐ＜０．０５）。提示：原发性高血压中存在以高胰岛素血症为中心的多代谢紊乱，对高血压、动脉硬化的发生、发展起重要作用。

Plasma insulin,glucose,lipidemia concentration were determined in 41 patients with hyperten-sion, 36 patients with hyperlipidemia,and 37 normal men。 Fasting glueose of all patients were nor-mal.The results showd that insulin levels demonstrated a signifieant increase and insulin resistnce inpatient with essential hypertension.High blood pressure ,hyperinsulinemia,insulia resistence, hyper-triglyceridemia,and a low plasma HDL-eh, which are called Reaven’s syndrome, exist in patient with hypertension。LDL-ch/HDL-ch(atheroselerosis idex ) was the highest among these three groups. Thissuggests that hyperinsulinmia may play an important role in the pathogenesis of hypertension andatheroselesosis.