化学产品过程开发实验平台——公斤实验室的建设和应用

Implementation and application of a kilo-lab for chemical products design and process development

以化工产品设计和过程开发为导向,建立了一个化工产品过程开发实验平台———化工产品公斤实验室Kilo lab。该公斤规模试验装置可进行反应、结晶、分离、提纯等系列产品的开发过程,研究了流程装置集成和柔性生产系统的规律和特征,为小批量、多品种、高附加值化学产品快速响应市场的变化和需求,以及过程开发的工业化放大提供理论和实验依据。

A laboratory platform for process development of chemical products, namely a kilo-lab, is established to integrate design for the chemical product and process development, which consists of mini operation units of reactors, a crystallizer, distillation columns, and dryers on a liter scale, to produce chemical products on a kilogram scale. The integration of process operations and product quality control is investigated. And the kilo-lab could provide a theoretical and experimental basis for chemical products of high added value in a small batch, to response to various needs for fine chemical products on the market promptly, as well as for an industrialized scale-up in the process development.