中越猕猴桃根提取物的体外抗肿瘤活性研究

Experimental Study on the Antitumor Effects of Extracts from Roots of Actinidia indochinensis in Carcinoma Cell Lines

目的:观察中越猕猴桃根提取物对肿瘤细胞株生长抑制的影响。方法:采用MTT比色法、集落形成法和生长曲线法测定中越猕猴桃根提取物对人胃癌细胞株SGC7901、白血病细胞株L1210和P388D1、宫颈癌细胞株He la、人肝癌细胞株Hele7404、黑色素瘤细胞株B16和神经肿瘤细胞株NG108- 15生长的抑制影响。结果:中越猕猴桃根提取物对 6种类肿瘤细胞株的生长均有不同程度的抑制作用。结论:中越猕猴桃根提取物在体外具有抗多种肿瘤作用。

Objective: To observe rhe effects of extracts from roots of Actinidia indochinensis on the growth inhibition in carcinoma cell lines Methods: The growth inhibition was analyzed by MTT, cell colony and cell growth curve measurement in the stomach carcinoma SGC7901,lymphocytic leukemia L1210,lymphoid neoplasm P338D 1, tumor of cervix uteri Hela, hepar carcinoma hele 7404,melanoma B16 and mouse neuroblastoma x rat glioma hybrid NG108 15 cells lines Results: The growth of all tumor cells were inhibited by extracts from roots of Actinidia indochinensis in all cell lines Conclusion: The results showed that extracts from roots of Actinidia indochinensis possessed the role of antitumors in cell culture