摘要
研究目的探讨丙戊酸钠治疗躁狂症的临床疗效及副反应。研究背景有报道丙戊酸钠具有抗躁狂作用,但与碳酸锂比较有何差异未见报道。研究方法病例对照研究。结果丙戊酸钠治疗躁狂症的临床疗效与碳酸钠无显著差异(P>0.05),丙戊酸钠副反应略高于碳酸锂。结论丙戊酸钠对躁狂症有治疗作用,可作为锂盐治疗无效的备选药或作为治疗躁狂症的合并用药。
Objective To search tbr the clinical effect and side - effects of sodium valproate in the treatment of mania disordor.Background The anti-mania effect of sodium valproate has been reporteo, but compared study between sodium valproate with lithium cathonate in the trearment of mania has not been investigated yet.Methods Case-controlled research.Results The anti-mania ettect nas no significant difference between sodium valproate and lithium carbonate (P>0.05). However the sideeffects of sodium valproate was lightly more serious than that of lithium carbonate.Conclution Sodium valproate has anti - ma-nia effect. It can be used as a alternative when lithium carbonate had no effect, or used as a combined medicine in treatment of mania.
出处
《新乡医学院学报》
CAS
1994年第1期57-59,共3页
Journal of Xinxiang Medical University
关键词
躁狂症
丙戊酸钠
碳酸锂
药理
疗效
mainic disorder
sodium valproate
lithium carbonate