反演与拟合相结合处理核磁共振弛豫数据的方法

Combination of inversion and fitting as an effective method for the analysis of NMR relaxation data

讨论非负最小二乘 (NNLS)法和非线性拟合在分析处理核磁共振 (NMR)弛豫数据中的应用 .同时将二者结合 ,提出用NNLS的反演结果来设定非线性拟合初值的方法 ,并用计算机模拟和实验证明了该方法在分析处理NMR弛豫数据中的有效性 .

A method is proposed for analyzing the NMR relaxation data. The procedure includes using the nonnegative least-squares (NNLS) to determine roughly the relaxation time values. Then those values are used as the initial parameters of the nonlinear fitting computation. As a result, accurate relaxation time data can be conveniently obtained without any pre-knowledge of the sample. This method is verified and demonstrated by computer simulations and NMR experimental results.