摘要
51例海洛因成瘾者,男性46例、女性5例。年龄为28±s5a(17-40a)。前3d根据近1wk内海洛因吸注量,用二氢埃托啡40-100μg于10%葡萄糖液500mL静脉滴注,4-6次/d,d3起加用丁丙诺啡0.3mg,im,q6h共4d。多数戒断症状如攻击行为、威胁、恶心、呕吐、腹泻于d1即消失,7d内所有戒断症状消退、未发现用药成瘾患者。
Fifty-one patients(M 46, F5;age 28±s 5 a)with heroinomania received dihydroetorphine 40-100μg in 10% glucose 500 mL iv,gtt for 4-6 times daily on d 1-3according to the amount of heroin consumed in the preceding week.From d 3 on additional buprenorphine 0.3 mg,im,q 6 h was injected for 4 d.Most abstinence symptoms such as attack behavior, threat, nausea,vomiting,diarrhea disappeared on d 1.All abstinence symptoms abolished within 7 d.No addict to such therapy was found.
出处
《新药与临床》
CSCD
北大核心
1994年第5期283-284,共2页
关键词
二氢埃托啡
丁丙诺啡
海洛因依赖
dihydroetorphine
buprenorphine
heroin dependence
combination drug therapy