慢性肾炎与乙型肝炎患者的免疫状态

Observation of immune state of patients with chronic nephritis and hepatitis B by lymphocyte B numbers

目的探讨慢性肾炎、乙型肝炎患者B淋巴纳胞的变化。方法通过小鼠红细胞玫瑰花结（M—RFC）试验，检查慢性肾炎、乙型肝炎患者和正常人的B淋巴细胞数，并同时检测免疫球蛋白及补体G3。结果慢性肾炎组B淋巴细胞数比正常组低，而乙型肝炎组明显比正常组高；两组Ig均普遍增高；两组C3均低于正常值。结论测定B淋巴细胞不但可以了解机体的体液免疫状态，也是证实T细胞或细胞免疫功能的另一途径。B淋巴细胞数的变化因疾病种类不同而有差异。

Objective To research the relation- ship between patients with the chronic nephritis and hepatitis B and the changes of the B Iymphocyte numbers.Methods Using the mice erythrocyte roset formation cell test (M- RFC), the B Iymphocyte numbers were examined in patients with chronic nephritis, hepatitis B and normal persons. Immunoglobulin and complement c3 were simultaneously examined. Rusults It is shown that the B lymphocyte numbers are lower in chronic nephritis than in normal group, and that of hepatitis B are higher than that of normal group. Immunoglobulin value are higher and complement c3 are lower in two kinds illness than that in normal group.Conclusion The examination of B lymphocyte can not only understand the humoral immunity of organism, but also determine the other way of immunity function. The numbers of B lymphocyte are vary in different kinds of illness.