复方氟哌酸宫栓和药膜治疗宫颈糜烂对照研究

A control study about suppository and medical film of compound fluopemidicum acid for cervical erosion

目的为选择治疗宫颈糜烂的高效、简便、低毒或无毒副作用的药物和最佳剂型。方法176例宫颈糜烂患者随机分为药膜组和栓剂组，分别以复方氟哌酸药膜和栓剂进行治疗。以临床检查、细胞学检查及用药反应等项指标进行对照观察。统计学处理采用卡方检验。结果药膜组对宫颈糜烂总有效率为90.83％，栓剂组为76.79％、药膜组疗效优于栓剂组（P＜0.05）。结论复方氟哌酸的两种剂型均可用于治疗宫颈糜烂，用药量小，无全身毒副作用，造价低，操作简便。药膜是治疗宫颈糜烂较为理想的剂型。

Objective The aim of this study was to selecte drug with higher effect, lower toxic and easy to extend and its satisfactory dosage form for treatment of cervical erosion.Methods One hundred and seventy five patients with cervical erosion were randomly divided into 2 groups and treated with eitber medicinal film or suppository of compound fluopemidicum acid. The clinicaI examination and papanicolaou cytological test were carried out before and after treatment.The X2 test was used for statistical analysis.Result In treatment the simple cervical erosion, the group of medicinal film got a general cure rate 90. 83%, the group of suppository achieved a general effective rate 76. 79%. The therapeutical effects of medicinal film is beter than that of the suppository group (P < 0.05).Conclusion Two method can be used with lit tle dosage, cheaper, performed easilly, and have provided quite effective without systemic toxic and side action.The medicinal film is a satisfactory dosage fOrm in cure cervical erosion.