导管灌注化疗栓塞治疗肝癌55例临床分析

Clinical analysis of 55 cases of hepatocellular carcinoma treated with intraarterial chemotherapy and transcatheter arterial embolization

目的:为了解介入治疗对进行期肝癌的临床疗效。方法:本文分析了我院55例肝癌经导管灌注化疗及栓塞治疗的临床资料,随访48例。结果:48例中存活时间半年以上者36例,占75％,1年以上者16例,占33.3％,1年半以上者3例,占6.3％。其中单纯灌注化疗6例,存活超过半年者仅5例。灌注化疗+碘油栓塞(二联)15例,存活超过半年者13例,超过1年者6例。灌注化疗+碘油+明胶海绵栓塞(三联)23例,存活超过半年者18例,超过1年者10例,超过1年半者3例。结论:本法治疗肝癌有较好疗效,二联和三联疗法存活时间显著高于单灌疗法。

AIM To investigate the clinical effect of transcather arterial chemotherapy(TAE)on the advanced hepatocellular carcinoma(HCC)METHODS 55 cases of HCC were treated with intraartcrial chemotherapy and TAE,among whom 48 were taken follow-up.RESULTS Among 48 cases taken follow-up,36 of them survived more than 6 months(75%),16 survived more than 12 months(33.3 %)and 3 more than 18 months(6.3%).10 were received intraarterial injection of anti-cancer agent,among whom only 5 survived more than 6 months.Among 15 received intraanerial chemotherapy plus lipiodol 13 survived more than 6 months and 6 more than 12 months.Among the other 23 received intraatrerial chemotherapy plus lipiodol and TAE with gelatin sponge,18 survived more than 6 months,10 more than 12 months and 3 more than 18 months.CONCLUSIONS The regimen was effective on HCG.The survivdal cases of the patients treated with intraarterial chemotherapy plus TAE and/or lipiodol were significantly higher than that of them only treated with intraarterial injection of anticancer agents.