摘要
非胰岛素依赖型糖尿病有25例(男性13例,女性12例;年龄61±s10a),用格列喹酮治疗,开始剂量15-90mg/d,根据血糖调整剂量,最大量为270mg/d。治疗3mo。结果:空腹和餐后2h血糖、糖基化血红蛋白和24h尿糖均明显降低(P<0.01)。空腹和餐后2h血糖控制总有效率为80%。2例有轻度恶心。该药为安全有效的降糖药。
Twenty-five patients(M 13,F 12;age 61±s 10 a)of NIDDM were treated with gliquidone.The initial daily dose was 15-90 mg.which was adjusted consecutively according to the levels of blood glucose,with the maximum of 270 mg/d.They were treated for 3 mo.The total response rate was 80%.The fasting and 2-h postprandial blood glucose,GHb and 24-h urinary glucose were remarkably lowered after therapy(P<0.01).The fasting and 2-h postprandial blood glucose were controlled satisfactorily in 6 and 3patients,fairly satisfactory in 6 and 3.in 7 and 14,and remained unchanged in 6 and 5 patients,respectively.Mild nausca was the only adverse effect.Gliquidone is a safe and effective hypoglycemic drug.
出处
《新药与临床》
CSCD
北大核心
1994年第1期37-39,共3页
关键词
格列喹酮
降血糖药
糖尿病
gliquidone
hypoglycemic agents
non-insulin-dependent diabetes mellitus