细胞角蛋白20表达与膀胱移行细胞癌复发的关系

Expression of cytokeration 20 in the bladder transitional cell carcinoma of recurrence and evaluation their significance

目的 探讨细胞角蛋白 2 0 (CK2 0 )在膀胱移行细胞癌 (TCC)中的表达及临床意义。方法 应用免疫组化及图像分析技术检测 5 4例TCC中CK2 0的表达 ,并进行分组比较。结果 CK2 0的表达在有否复发组之间差异有极显著性意义 (P <0 .0 0 1)。结论 CK2 0的表达与TCC生物学行为密切相关 ,为临床预测TCC复发开辟了新方法。

Objective To investigate the expression of cytokeration 20 (CK20) in bladder transitional cell carcinoma (TCC).Methods The expression of CK20 was examined in 54 cases with TCC by immunohistochemical methods and image pattern analysis.Result CK20 expression was significantly different between recurrent group and non-recurrent group(P<0.001).Conclusion The expression of CK20 is significantly related to biological behavior of TCC,that provides some new ways for clinical predict to recurrence of TCC.