摘要
甲红霉素治疗呼吸道感染64例(男性38例,女性26例;年龄44±s17a)。用法为0.25g,bidpo,疗程7-14d,有效率为97%,细菌清除率为94%,不良反应发生率为12%。分离菌药敏显示,对呼吸道感染常见病原菌具良好的抗菌作用,对流感杆菌作用优于红霉素等大环内酯类。
Clarithromycin was given to 64 patients(M 38, F 26;age 44±s 17 a) with respiratory tract infections at the oral dosage of 0.25 g,bid for 7-14 d.Results showed the total effective rate was 97%,the bacteriologic eradication rate was 94%,and adverse reactions rate was 12%.The microbial in vitro sensibility test on isolates indicated that clarithromycin has good activity on bacteria responsible for respiratory tract infections and is more potent against H influenzae than other macrolides including erythromycin.
出处
《新药与临床》
CSCD
北大核心
1994年第5期258-261,共4页
关键词
甲红霉素
呼吸道感染
药物评价
clarithromycin
respiratory tract infections
microbial sensitivity tests
drug evaluation