垂体腺瘤经颅手术死亡因素探讨

Study of the Mortality Factors of Transcranial Operations for Pituitary Adenomas

目的:探讨垂体腺瘤经颅手术后死亡原因,以降低手术死亡率。方法:对537例经颅垂体腺瘤手术中的12例术后死亡病例进行回顾性分析。结果:6例死于术后颅内出血,5例死于下丘脑损伤,1例死于突发呼吸停止。死亡率为0.2%。结论:术后颅内出血和下丘脑损伤足垂体腺瘤经颅手术后死亡的主要原因,应采用相应措施,降低死亡率。

Aim: To explore the causes of transcranial postoperative death in patients with pituitary adenomas to reduce operation mortality. Methods: 12 death cases of 537 pituitary adenomas with transcranil operations were analyzed retrospectively. Results: 6 cases died from postoperative intracranial hemorrhage; 5 cases died from hypothalamus injury; 1 cases died from sudden respiratory arrest. Operation mortality is 0.2 % . Conclusion: Postoperative intracranial hemorrhage and hypothalamus injury are the major causes of transcranial postoperative death in the patients with pituitary adenoma. Appreciate preventive measures should be taken to reduce mortality of operation.