Tankyrase——一种多功能的端粒结合蛋白
Tankyrase-a multi-functions telomere-binding protein
摘要
Tankyrase是一种与人类端粒有关的二磷酸腺苷核糖多聚合酶,最早是通过与 TRF1结合而被发现,是人类端粒的正性调节因子。近几年研究发现,有丝分裂期的核孔复合物、中心体,减数分裂期的纺缍体和分裂间期的高尔基体也存在着大量Tankyrase,提示Tankyrase是一种多功能蛋白。现就Tankyrase和Tankyrase2的结构和功能作一综述。
出处
《国外医学(临床生物化学与检验学分册)》
2005年第1期18-20,共3页
Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
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