链蛋白在乳腺癌中表达的研究进展
摘要
链蛋白(Cats)是一组具有相似结构的胞内糖蛋白家族,能与上皮钙粘蛋白(E Cad)胞内结合,共同承担上皮细胞的粘附和信号转导功能,在细胞的粘附、核转移、生长控制以及肿瘤的发生中起重要作用。许多肿瘤的发生、发展均涉及链蛋白的基因突变、表达异常。为进一步揭示乳腺癌的分化、侵袭机制,现就乳腺癌的发生、转移、预后及与链蛋白的关系作一综述。
出处
《国外医学(临床生物化学与检验学分册)》
2005年第1期49-50,53,共3页
Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
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