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链蛋白在乳腺癌中表达的研究进展

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摘要 链蛋白(Cats)是一组具有相似结构的胞内糖蛋白家族,能与上皮钙粘蛋白(E Cad)胞内结合,共同承担上皮细胞的粘附和信号转导功能,在细胞的粘附、核转移、生长控制以及肿瘤的发生中起重要作用。许多肿瘤的发生、发展均涉及链蛋白的基因突变、表达异常。为进一步揭示乳腺癌的分化、侵袭机制,现就乳腺癌的发生、转移、预后及与链蛋白的关系作一综述。
出处 《国外医学(临床生物化学与检验学分册)》 2005年第1期49-50,53,共3页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
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  • 1Aho S,Levansuo L,Montonen O,et al.Specific sequences in p120ctn determine subcellular distribution of its multiple isoforms involved in cellular adhesion of normal and malignant epithelial cells.J CellSci,2002,115(Pt 7):1391-1402.
  • 2Anastasiadis PZ,Reynolds AB.The p120 catenin family:complex roles in adhesion,signaling and cancer.J Cell Sci,2000,113 ( Pt 8):1319-1334.
  • 3Jonsson M,Borg A,Nilbert M,et al.Involvement of adenomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer.Eur J Cancer,2000,36(2):242-248.
  • 4Gilles C,Polette M,Mestdagt M,et al.Transactivation of vimentin by beta-catenin in human breast cancer cells.Cancer Res,2003,63(10):2658-2664.
  • 5Dillon DA,D'Aquila T,Reynolds AB,et al.The expression of p120ctn protein in breast cancer is independent of alpha- and beta-catenin and E-cadherin.Am J Pathol,1998,152(1):75-82.
  • 6Rimm DL,Caca K,Hu G,et al.Frequent nuclear/cytoplasmic localization of beta-catenin without exon 3 mutations in malignant melanoma.Am J Pathol,1999,154(2):325-329.
  • 7Schlosshauer PW,Brown SA,Eisinger K,et al.APC truncation and increased beta-catenin levels in a human breast cancer cell line.Carcinogenesis,2000,21(7):1453-1456.
  • 8Miyoshi K,Hennighausen L.Beta-catenin:a transforming actor on many stages.Breast Cancer Res,2003,5(2):63-68.
  • 9Mao TL,Chu JS,Jeng YM,et al.Expression of mutant nuclear beta-catenin correlates with non-invasive hepatocellular carcinoma,absence of portal vein spread,and good prognosis.J Pathol,2001,193(1):95-101.
  • 10Shah S,Pishvaian MJ,Easwaran V,et al.The role of cadherin,beta-catenin,and AP-1 in retinoid-regulated carcinoma cell differentiation and proliferation.J Biol Chem,2002,277(28):25313-25322.

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