自然流产与TORCH感染相关性分析

Association between the natural abortion and TORCH infection

目的 探讨杭州地区自然流产与弓形体(TOX)、风疹病毒(RV)、巨细胞病毒(CMV)和单纯疱疹病毒 (HSV)4种病原体(简称TORCH)感染的相关性。方法 选择2000年10月～2003年10月自然流产孕妇,用酶 联免疫吸附试验(ELISA)分析TORCH各项IgM,与同时间段正常育龄孕妇TORCHIgM进行比较,探讨自然流产 与TORCH感染的关系。结果 自然流产孕妇TOX、RV、CMV和HSVIgM抗体阳性率分别为14.47%、11.18%、 25.66%和3.95%。而同时段正常育龄孕妇相应的IgM抗体阳性率为0.11%、0.29%、0.50%和0.16%。自然 流产孕妇TORCH各项IgM阳性率均显著增高(P<0.01)。结论 孕妇TORCH感染是自然流产的重要原因。

Objective To study the association between the spontaneous abortion and Toxoplasma(TOX), Rubella virus(RV), Cytomegalovirus(CMV), Herpes simplex virus(HSV)(TORCH) infection in Hangzhou area. Methods Pregnant women with natural abortion from Oct. 2000 to Oct. 2003 were studied IgM antibodses to TORCH were tested by ELISA. Results In the pregnant women with natural abortion positive rates of IgM antibody to TOX,RV,CMV and HSV were 14.47%,11.18%, 25.66% and 3.95% respectively. While the relevant IgM antibody positive rates of healthy pregnant women in the same period were 0.11%,0.29%,0.50% and 0.16% respectivetly. Positive rates of all IgM antibody to TORCH pathogen in natural abortional pregnant women were remarkable high(P<0.01). Conclusions TORCH infection is the important cause of natural abortion.