一日龄小鸡的记忆保持及其与脑内加压素（AVP）含量的相关研究

VASOPRESSIN AND MEMORY RETENTION IN ONE-DAY OLD CHICKS

以一日龄小鸡为实验对象，进行一次性厌恶回避反应训练，并应用加压素的放射免疫测定法，分析比较记忆保持测验中，成绩优、劣及对照组动物与其脑内加压素含量的相关。实验结果表明，记忆保持良好的动物，脑内加压素含量明显低于对照组和记忆不良组，而记忆不良组与对照组之间则无明显差异。提示在正常生理状态下，加压素参与记忆过程的调制，并可能在这一过程中有一定的耗竭或合成减少，如适时得以补充，则对记忆的巩固和再现起易化作用。

One-day old chicks were trained in a single-trial passive avoidance task.Based on the performance of memory retention, the chicks were divided into wo groups.AVP levels of the chick brains of each group were measured by using radioilmmunoassay.The results showed the AVP level in the good performance group was significantly lower than that in both the bad performance group and the control group. However, there were no significant differences in the AVP level between the bad performance group and the contrast group.The result suggested that the endogenous AVP might have been consumed in the memory process.