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CD4分子二聚化或寡聚化的研究进展 被引量:3

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作者 肖鹤 黎燕
出处 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2005年第B03期28-30,共3页 Chinese Journal of Cellular and Molecular Immunology
基金 国家重点基础研究发展规划(973)资助(No. 2003CB515508)
关键词 CD4 二聚化 寡聚化
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  • 1Wang JH, Yan YY, Garrett TPJ, et al. Atomic structure fo a fragment of human CD4 containing two immunoglobulin-like domains[J]. Nature, 1990, 348(29): 411-418.
  • 2Ryu SE, Kwong PD, Truneh A, et al. Crystal structure of an HIV-binding recombinant fragment of human CD4[J]. Nature, 1990, 348(29): 419-425.
  • 3Hussey RE, Richardson NE, Kowalski M, et al. Production of a soluble CD4 protein that selectively inhibits human immunodeficiency virus replication and syncytium formation[J]. Nature, 1988, 331: 78-81.
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  • 6Wu H, Kwong PD, Hendrickson WA. Dimeric association and segmental variability in the structure of human CD4[J]. Nature, 1997, 387(29): 527-530.
  • 7Lynnch GW, Sloane AJ, Raso V, et al. Direct evidence for native CD4 oligomers in lymphoid and monocytoid cells[J]. Eur J Immunol, 1999, 29: 2590-2602.
  • 8Lynnch GW, Slaytor EK, Elliott FD, et al. CD4 is expressed by epidermal Langerhans' cells predominantly as covalent dimers[J]. Experimental Dermatology, 2003, 12(5): 700-711.
  • 9Moldovan MC, Yachou A, Levesque K, et al. CD4 dimers constitute the functional component required for T cell activation[J]. J Immunol, 2002, 169: 6261-6268.
  • 10Toth PT, Ren D, Miller RJ. Regulation of CXCR4 receptor dimerization by the chemokine SDF-1α and the HIV-1 coat protein gp120: a fluorescence resonance energy transfer (FRET) study[J]. J Pharmacol Exp Ther, 2004, 310(1): 8-17.

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