摘要
观察12例心律失常病人不同频率(70,90及110ppm)AAI和VVI起搏时的心排出量(CO)、心脏指数(CI)、肺毛细血管楔嵌压(PCWP)、肺动脉压(PAP)、右房压(RAP)和血浆心钠素(ANP)、肾素活性(PRA)及血管紧张素II(A-II)的变化。结果显示:AAI起搏时,CO、CI显著高于VVI起博和较慢的自身窦性心律时(P<0.05或0.01),而无VVI起搏所引起的PCWP、PAP、RAP、ANP、PRA及A-II等显著增高缺点。提示AAI起博具有良好的血液动力学效应且不导致心脏内分泌激素异常而优于VVI。
Twelve patients with cardiac arrhythmias underwent Swan-Ganz catheterization during pacemaker implanta tion.AAI and VVI pacing were performed consecutively at three pacing rate levels(70,90,110 ppm).Cardiac output(CO),cardiac index(CI).pulmonary capillary wedge pressure(PCWP),pulmonary artery pressure(PAP),right atrial pressure(RAP).atrial natriuretic peptide(ANP).plasma renin activity(PRA)and angiotensin-II (A-II)were measured during different pacing modes and rates.The results showed that AAI pacing caused a significant increase(P<0.05,P<0.01)of CO and CI as compared with VVI pacing and as slower sinus rhythm,no slgnificant changes of PCWP,PAP,RAP,ANP.PRA and A-II were observed.The observation suggested that there could be benefit effects of AAI pacing on hemodynamics but without influence on cardiac endocrine hormone.
关键词
心脏起搏
血液动力学
心钠素
肾素
血管紧张素
cardiac pacing
Hemodynamics
Atrial natriuretic peptide
Renin- angiotensin system