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施多宁、佳息患联合治疗与国产药三联治疗艾滋病6个月疗效比较 被引量：2

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摘要 目的比较施多宁、佳息患联合治疗方案与国产药物去羟基苷散、司他夫啶和奈韦拉平三药联合方案治疗艾滋病(AIDS)病人6mo时的疗效及不良反应。方法26例AIDS，给子施多宁、佳息患联合治疗；对照组AIDS38例，给予国产药物去羟基苷散、司他夫啶和奈韦拉平三药联合方案，均随访6mo，监测病人的血浆人类免疫缺陷病毒(HIV)病毒载量及CD4^+T淋巴细胞计数，并评价药物不良反应。结果经过6mo治疗两组病人血浆中HIV RNA含量均明显降低(P<0.01)，CD4^+T淋巴细胞数量增加(P<0.01)，药物不良反应轻微。结论施多宁、佳息患联合治疗组和国产药物三联治疗组均能有效抑制HIV复制，机体免疫功能亦有改善。
作者 卢洪洲 蒋卫民 张彤 吴吴 李在村 胡越凯 薛以乐 潘启超 尹春煜 潘孝彰 康来仪
机构地区 复旦大学公共卫生中心传染科 复旦大学附属华山医院传染科 首都医科大学附属北京佑安医院 上海市疾病预防控制中心
出处 《世界感染杂志》 2005年第1期41-44,共4页 World Journal of Infection
关键词 施多宁 国产药 联合治疗 三联治疗 AIDS HIV 艾滋病 RNA 羟基 复制
分类号 R512.91 [医药卫生—内科学] R978.7 [医药卫生—药品]
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参考文献10

  • 1Yang QE. Eradication of HIV in infected patients: Some potential approaches[J]. Med Sci Monit, 2004, 10(7): 155-165.
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  • 6卢洪洲,胡越凯,薛以乐,潘启超,何云,赵清霞,尹春煜,蒋为民,潘孝彰,翁心华,康来仪.去羟肌苷散、司他夫定和奈韦拉平联合治疗艾滋病患者6个月疗效观察[J].临床内科杂志,2004,21(4):258-260. 被引量：6
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二级参考文献7

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世界感染杂志
2005年 第1期

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