前列腺增生患者尿流率及其影响因素的关系

Uroflowmetry and its influence factors in benign prostate hyperplasia patients

目的:探讨前列腺增生患者的病程、年龄、排尿前膀胱容量、前列腺移行区指数以及增生腺体间质腺 体面积百分比等各参数与相应的尿流率的关系。方法:对89例前列腺增生患者运用数字图像分析、经肛B超和尿 流动力学等检查方法测定各参数的值,用逐步回归法分析尿流率及其影响因素的关系。结果:尿流率与排尿前膀 胱容量呈正相关(r=0.477,P<0.01),与增生腺体间质腺体面积百分比亦呈正相关(r=-0.437,P<0.05),而与 年龄、病程和移行区指数没有相关性(P>0.05);所有患者前后3次排尿所得尿流率/排尿前膀胱容量这一参数差 别没有统计学差异(P>0.05)。结论:尿流率与膀胱容量之比这一参数可用来评价尿量少于200ml前列腺增生患 者排尿方面的改变;对前列腺增生患者的药物治疗,α受体阻滞剂的应用应受到相当的重视。

Objective To determine the relationship between uroflowmetry and age, the course of disease, premicturition volume, transition zone index and proportion of stroma-to-epithelium in benign prostate hyperplasia (BPH) patients. Methods Eighty-nine BPH patients in our hospital from 2000 to 2003 were evaluated. With the CMM3 pathology image analysis system, transrectal ultrasound and Dantec 2000 urodynamic instrument, the value of influence factors was determined. A linear regression was applied to analyze all the data by SPSS software. Results The flow rate was correlated to premicturition volume (r=0.477,P<0.01) and proportion of stroma-to-epithelium significantly (r=-0.437,P<0.05), but was not correlated to the age, the course of disease and transition zone index significantly. The parameter of flow rate/premicturition volume had no difference in 3 micturitions in all patients. Conclusion The parameter (flow rate/premicturition volume)could be used to evaluate the micturition status of the BPH patients whose bladder volume is less than 200ml. We should pay more attention to receptor blockers when we treat BPH patients.