大孔吸附树脂富集雷公藤内酯醇的研究

Study on macroporous adsorbing resin for purification of triptolide

目的:应用大孔吸附树脂D101型分离、纯化雷公藤内酯醇。 方法:用醇提水沉后,经D101树脂吸附及氧化铝柱除杂,用 95%乙醇解吸,高压液相色谱(HPLC)测定含量。 结果:雷公藤内酯醇可得到较好的保留。 结论:D101可应用于雷公藤内酯醇的富集。

Objective: To apply D101 macroporous resin for separation and purification of triptolide. Methods: After extracted by alcohol the extracts were dissolved in water and passed through a macroporous resin column and a aluminum oxide column. Then the triptolide on the columns were eluated with 95% alcohol and determination by HPLC. Results:Triptolide could be retained on D101 column. Conclusion: D101 resin can be used to refine the triptolide.