宁德地区孕妇TORCH感染的调查分析

The investigation and analysis of TORCH infection in pregnant women of Ningde district .

目的 调查宁德地区孕妇TORCH的感染率。方法 采用抗体捕获ELISA的检测方法 ,对 2 0 0 1年 7月至2 0 0 3年 7月来我院产前检查并自愿接受TORCH检测的孕妇 1 81 2例检测了TORCH -IgM抗体。结果 (1 )TORCH -IgM总阳性率为 1 8.33% ,弓形虫 (TOX)、风疹病毒 (RUV)、巨细胞病毒 (CMV)、单纯疱疹病毒 (HSV -I)、(HSV -II)IgM阳性率分别为 5 .30 %、4 .6 4 %、3.5 3%、2 .2 1 %、2 .6 5 % ;(2 )有异常妊娠史的孕妇TOX -IgM、RUV -IgM明显高于无异常妊娠史的孕妇 ;(3)调查发现宁德地区TORCH的不同病原体感染具有不同的季节性。春夏季节弓形虫感染率高、夏秋季节风疹病毒感染率高、巨细胞病毒在冬季感染率最低 ,单纯疱疹病毒的感染季节性不明显。结论 TORCH感染与优生优育有重要关系 ,建议在孕前进行TORCH感染筛查 ,不同季节重视高发病原体感染的预防 ,计划受孕 ,对优生学具有现实意义。

Objective: A Survey of the TORCH infection rate among pregnant women in Ningde District. Methods: 1812 pregnant women who came to Ningde Municipal Hospital for medical examination before delivery had their antibody of TORCH-IgM tested from July of 2001 to July of 2003, with the method of Antibody Capture ELISA.Results: (1) The total positive rates of TORCH-IgM was 18.33%, and the positive rate of toxoplasma(TOX),rubella virus (RUV), cytomegalovirus (CMV),herpes simplex virus-I (HSV-I), herpes simplex virus-II (HSV-II) accounted for 5.30%,4.64%,3.53%,2.21%,2.65% respectively. (2) Among those pregnant women who had experienced abnormal pregnancy, the infection rate of TOX-TgM and RUX-IgM was obviously higher than in those who didn't experience it. (3)The survey showed the TORCH infection rate of different pathogens was seasonal: in spring and summer, TOX's infection rate was high while RUV's was high in summer and autumn, and the infection rate of CMV was lowest in winter but HSV-I and HSV-II IgM didn't show obvious seasonalness. Conclusion: The infection of TORCH relates importantly to the plan of aristogenesis. Here we suggest a test of TORCH-IgM antibody before being pregnant, paying attention to the prevention of highly infected pathogen and good planning of impregnation, because all these have practical meaning to eugenics.