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HL-91延迟显像在乳腺良恶性病变鉴别诊断中的价值 被引量:2

The Value of HL-91 Delay Imaging in the Diagnosis of the Breast Disease
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摘要 目的:探讨HL 91延迟显像及半定量分析在乳腺癌诊断中的价值。方法:52例早期HL 91显像有 局灶性放射性增高的病人在注射显像剂6h后再进行延迟显像,根据延迟显像变化,病人分为两组:A组34例 延迟显像UR值变化不大,与早期显像UR值相比(P>0.05);B组18例延迟显像UR值明显降低或病灶消失, 与早期显像UR值相比(P<0.05)。两组病例进行随访。结果:经病理及临床最后证实A组均为乳腺癌,B组 均为良性病变。结论:延迟显像及半定量分析可提高乳腺良恶性病变诊断的准确性。 Objective:To explore the value of the HL-91 delayed imaging and semi-quantitave analysis method for the diagnosis of breast cancer. Methods:52 patients who had abnormal hypermetabolic foci for HL-91 early imaging underwent delayed image at 6 hours after injection. Patients were divided into two groups by the uptake ratio (UR) of L/N in the HL-91 delayed imaging. Group A(34 cases) included patients who had unchanged or increased UR value in the HL-91 delayed imaging as compared with early imaging. UR values of Group B(18 cases) decreased and were significant different with regard to their early imaging results(P<0.05).We followed up all of the patients by operation and pathology. Results:All of patients in group A were with breast cancer confiormed through biopsy, and were with benign diseases of the breast in group B. Conclusion:In the HL-91 scanning,the delayed image semi-quantitave analysis methods could improved the diagnostic accuracy greatly for the detection of breast neoplasms.
出处 《广州医学院学报》 2004年第4期39-41,共3页 Academic Journal of Guangzhou Medical College
关键词 乳腺肿瘤 放射性核素显像 HL-91 延迟显像 诊断 breast neoplasms radionuclide imaging HL-91 delayed image diagnosis
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参考文献4

  • 1Yutani K, Kusuoka H, Fukuchi K, et al. Applicability of 99Tcm-HL91, a putative hypoxic tracer, to detection of tumor hypoxia [J]. J Nucl Med, 1999,40 (5) :854 - 861.
  • 2Cook GJR, Houston S, Barrington SF, et al. 99Tcm-HL91 to identify tumor hypoxia: Correlation with 18F-FDG [J]. J Nucl Med, 1998,39(1) :99 - 103.
  • 3Van De Wiele C, Versijpt J, Dierckx RA, et al. 99Tc(m)labelled HL91 versus computer tomography and biospy for the visualization of tumour recurrence of squamous head and neck carcinoma[J]. Nucl Med Commun,2001,22(2) :269- 275.
  • 4李莉,韩佩珍,阎玉军,王月英,王俊起,李美佳.小鼠恶性淋巴瘤^(99)Tc^m-HL91显像实验研究[J].中华核医学杂志,2002,22(2):118-119. 被引量:10

二级参考文献1

  • 1Mitsuaki Tatsumi,Kenji Yutani,Hideo Kusuoka,Tsunehiko Nishimura. Technetium-99m HL91 uptake as a tumour hypoxia marker: relationship to tumour blood flow[J] 1999,European Journal of Nuclear Medicine(2):91~94

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