儿童下呼吸道肺炎支原体感染临床分析

Clinical analysis of Mycoplasma Pneumoniae infection in children

目的 为进一步分析目前儿童下呼吸道肺炎支原体感染特点,及其占总下呼吸道感染的发生率,以提 高对该病临床诊治水平。方法 对本院诊治的78例下呼吸道肺炎支原体感染的病例进行临床和实验室分析。结 果 支原体感染以婴幼儿、学龄前儿童多见,其中婴幼儿20例,占25.64％;学龄前儿童33例,占42.30％;总体病 情较轻,并发症少,胸部X线表现局部斑片状和网点状阴影占优势。与其他年龄组相比,3岁以下患儿喘息及肺部 罗音发生率较高(P<0.05);6岁以上儿童肺外并发症发生率较高(P<0.05)。支原体IgM多在病程8-10天被检出 (69.23％)。末梢白细胞总数正常率为80.76％;中性粒细胞分类>50％者占53.84％。C反应蛋白(CRP)升高率为 51.27％。结论 儿童下呼吸道肺炎支原体感染发病年龄趋于小龄化、总体病情虽轻、但不同年龄儿童发病有其不 同特点,抗体检出时间往往滞后于临床症状,外周血常规检查及CRP水平无特异性。临床医生应提高对本病认识。

Objective To highlight the clinical features and ratio of mycoplasma pneumoniae (Mp) in lower respiratory infection in children. Methods We've collected and analyzed the data of 78 inpatient children, aged between one month and 12 years, ailed with lower respiratory infection. The data include clinical manifestation and examination, blood cell count and its classification, and detecting of concentrations of Mp antibody in blood. Results Mp infection is more likely occurred in infant (20/78, constituted 25.64%), toddles and the young children(33/78,42.30%). In generally, the symptoms were mild, X-ray often showed the local stains or net spots shadows. Compared with other patients, whoop and rale were more likely to be heard in below 3 years old (P<0.05); Complications were prone to attack the elders, over 6 years old (P<0.05). Mp-IgM antibody often appeared in 8th days. Peripheral blood WBC count were usually in normal range (constituted 80.76%). Creactive protein (CRP) levels were increased in 51% overall. Conclusions The age of children with lower respiratory Mp infection tends younger. Although it's not serious in most patients, Mp infection in different ages had different features. Mp-IgM antibody is of diagnostic value, but often lagged than clinical manifestations.