肺黏膜相关型淋巴瘤的临床研究(附5例报告)

A clinical study of Pulmonary mucosa associated lymphoid tissue lymphoma: a report of 5 cases

目的 为提高对肺黏膜相关型淋巴型(MALT淋巴瘤)临床特征的认识。方法 经我院确诊的肺MALT 淋巴瘤5例,进行回顾性的临床分析研究。结果 ①本组5例均为肺低度恶性MALT型淋巴瘤。②临床上5例病 人均有吸烟、反复肺部感染等慢性免疫系统刺激因素存在。③肺MALT型淋巴瘤与肺炎性假瘤关系密切,临床症 状缺乏特异性。结论 肺MALT淋巴瘤是非霍奇金淋巴瘤的一种独特亚型,而且容易误诊,疗效和预后较好。

Objective To have a better understanding of the clinical characteristics pulmonary mucosa associated lymphoid tissue lymphoma (PMALTL). Methods The information of diagnosis, pathological characteristics, treatment and prognosis of PMALTL and the clinical data of 5 cases were collected and analysied. Results All of the 5 cases were diagnosed pathologically as low grade small B cell PMALTL. There were history of smoking and recurrent pulmonary infection in 5 patients as preexisting chronic immune system stimulation. PALTL should be differentially diagnosed because of the closed relationship between the two dieases, and there is no marked clinical feature Conclusions MALT lymphoma is an indolent disease that presents in localized extranodal location without any associated adverse prognostic factor, these patients have a high reponse rate to treatment and long survival.