摘要
目的 验证抑郁症和失眠症同源性假说。方法 采用多导睡眠图记录仪,记录并分析30例抑郁症患者和30例失眠症患者整夜的脑电图、眼电图、肌电图等。结果 抑郁症患者快动眼(REM)睡眠明显活跃,各项 REM指标均与失眠症患者有非常显著性差异( P <0.01);失眠症患者以睡眠持续性差、浅睡和觉醒增多以及深睡和REM睡眠明显受抑制为特征,不少患者的整个慢波睡眠(S3+S4)缺失。结论 抑郁症与不伴抑郁情绪的失眠症睡眠模式不同,抑郁症以 REM睡眠过度活跃为特征,而失眠症以非REM睡眠明显紊乱为主要特征。
ObjectiveTo verify the homology hypothesis of depression and insomnia.MethodsAll night physiological signals of electroencephalogram (EEG), electrosculogram (EOG) and electromyogram (EEG) of 30 depression cases and 30 insomnia cases were recorded and analyzed with polysomnogram.ResultsThe rapid eye movement (REM) sleep of depression patients was more active, and there was a significant difference in all REM indexes compared with insomnia cases ( P<0.01). Characteristics of insomnia cases were poor sleep continuity, easy wake after sleep onset, and depression of slow wave sleep and REM sleep. There was no slow wave sleep in some insomnia cases.ConclusionThe sleep patterns of depression and insomnia are different, REM sleep is hyperactive in depression; non REM sleep is disturbance in insomnia. [
出处
《中国康复理论与实践》
CSCD
2005年第2期135-136,共2页
Chinese Journal of Rehabilitation Theory and Practice
基金
广东省医学科研基金(No. A2001588)
