摘要
伪狂犬病是由伪狂犬病病毒引起的多种畜、禽及野生动物的一种以发热、奇痒、脑脊髓炎为主要症状的急性传染病。该病每年给养猪业造成的损失达数十亿美元,目前对该病主要是以疫苗防制为主。随着基因工程技术的不断更新和发展,研制更加安全、有效的基因工程疫苗对该病的防治将会有重要的意义。文章对伪狂犬病基因缺失疫苗及活载体疫苗的研究进行了综述。
Pseudorabies is caused by Pseudorabies virus(PRV),which is a member of family herpesviridae and is the agent of acute infectious disease in many domestic and wild animals.Infection may result in signs ranging from clinically inapparent latent carrier states to fatal respiratory tract or neurologic disease syndromes.The virus is responsible for major economic loss in pig industries worldwide.Vaccination is one of the most effective prophylactic measure to prevent the disease. In this assay,research progress on PRV gene-deleted and virus vector vaccine used extensively today was discussed.
出处
《动物医学进展》
CSCD
2005年第3期19-22,共4页
Progress In Veterinary Medicine
