FLAIR序列在低场脑MRI中的应用研究

Application of fluid-attenuated inversion-recovery (FLAIR) sequences in low field strength MRI of the brain

目的 :探讨在低场MRI中FLAIR序列对颅脑疾病的临床应用价值。方法 :2 4 7例颅脑疾病患者 ,均进行FLAIR序列和FSE T2 WI检查 ,比较两种序列对病灶的显示能力。结果 :MRI共发现 5 1 6个病灶 ,FLAIR序列显示病灶 5 0 8个(98 4 4%) ,FSE T2 WI显示病灶 4 36个 (84 .5 0 %) ,两者在显示病变方面有显著差异 (P <0 .0 1 )。FLAIR序列显示病灶内部结构及边缘良好者为 2 80个 (5 5 .1 2 %) ,FSE T2 WI为 1 2 0个 (2 7.5 2 %) ,两者在显示病变内部结构及边缘清晰度方面 ,FLAIR序列优于FSE T2 WI(P <0 .0 1 )。结论 :在低场脑MR中 ,FLAIR技术对颅脑病变的显示优于常规FSE T2 WI,有助于提高病变的检出率 ,清晰显示病灶内部结构与边缘 ,可作为颅脑MRI检查的常规序列。

Objective:To evaluate the clinical application of FLAIR sequences in low field MRI of the brain.Methods:247 patients with brain diseases were studied with MR FSE-T 2WI and FLAIR technique.The detectable abilities of lesions with FLAIR and FSE-T 2WI were compared.Results:516 lesions were identified with MRI in 247 patients. The FLAIR imaging showed 508 lesions(98.44%), but the FSE-T 2WI only showed 436 lesions (84.50%).The difference is statistically significant (P<0.01).280 lesions were clear with FLAIR in demonstrating the intrinsic structure and border of lesions, and 120 ones with FSE-T 2WI. Therefore, the FLAIR imagings were superior to FSE-T 2WI in demonstrating the intrinsic structure and border of lesions (P<0.01).Conclusion:In low field MR of the brain, FLAIR was superior to conventional FSE-T 2 weighted sequence for patients with brain diseases. It is useful to improve the detection of the lesions and demonstrate the intrinsic structure and border of lesions clearly. FLAIR can be used as a conventional sequence of the examination in MRI of the brain.