Moyamoya病代偿血流的评价

Assessment of Collateral Circulation in Patients with Moyamoya Disease

目的 研究 Moyamoya 病不同侧支循环的血流动力学特点。方法 DSA诊断的 Moyamoya 病患者,依据有无大脑后动脉和颈外动脉代偿进行分组,对比大脑后动脉和颈外动脉的峰值血流速度和脉动指数或阻力指数。通过受试者工作特征曲线分析,确定TCD评估标准。结果 有大脑后动脉参与代偿时,大脑后动脉 Vp较高, PI较低 (P < 0.001)。有颈外动脉参与代偿时, RI 较低 (P <0.001)。结论 TCD可以帮助临床评价Moyamoya 病的代偿情况。

Objective To probe the hemodynamics characteristics of different collateral circulation in moyamoya disease. Methods Consecutive patients diagnosed with moyamoya disease by digital subtraction angiography were included. The statuses of collateral circulation were differentiated by digital subtraction angiography. Peak flow velocity and pulsatility index or resistance index of the posterior cerebral arteries and external carotid artery were compared in patients with and without collaterals. The receiver operating characteristic analysis was used to define transcranial Doppler criteria for distinct collateral status. Results The posterior cerebral arteries peak flow velocity was higher and pulsatility index was lower in patients with posterior collaterals (P<0.001). The external carotid arteries resistance index was lower in patients with external carotid collaterals (P<0.001). Conclusions Transcranial Doppler may help clinicians to differentiate collateral status of moyamoya disease.