异丙酚持续静滴治疗小儿癫持续状态的临床观察

Propofol infusion in the treatment of status epilepticus in children.

目的 总结异丙酚持续静滴治疗小儿癫持续状态的疗效。方法 对2 0 0 1年4月至2 0 0 3年10月唐山工人医院儿科8例继发性癫持续状态患儿的治疗进行分析,本组8例均为常规抗癫药物不能控制的继发性癫所致癫持续状态。在使用常规止惊药物失败后开始异丙酚静滴。结果 8例患儿全部抽搐停止。结论 癫持续状态是儿科急症之一,如何在短时间内控制癫持续状态是治疗成败的关键,在正确常规治疗无逆转时,应用异丙酚持续静滴可以有效控制癫持续状态且未见严重不良反应。

Objective To assess the efficacy of the use of propofol infusion for the treatment of the status epilepticus (SE) in children.Methods 8 patients chose from the deportment of pediatricso of our hospital from April 2001 to October 2003.All the 8 children with SE couldn't be controlled by routine anti-epileptic drug therapy and then were treated with propofol infusion.Results All the children successfully terminated the seizure with propofol infusion.Conclusion Propofol infusion is a safe and effective method in the treatment of SE without severe side effects.