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从肝星状细胞激活过程中的信号转导途径谈肝纤维化的干预措施 被引量:3

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出处 《中华医学杂志》 CAS CSCD 北大核心 2005年第10期719-720,共2页 National Medical Journal of China
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  • 1邓存良,陈国民,余光开,刘林.重组人白细胞介素-1受体拮抗剂抗肝纤维化的实验研究[J].中华微生物学和免疫学杂志,2000,20(2):140-141. 被引量:14
  • 2Di Sario A, Bendia E, Taffetani S, et al. Selective Na+/H+ exchange inhibition by cariporide reduces liver fibrosis in the rat. Hepatology,2003,37:256-266.
  • 3Powell EE, Edwards S, Hay JL, et al.Host genetic foctors influence disease progression in chronic hepatitis. Hepatology, 2000;31:828-833.
  • 4Furukawa F, Matsuzaki K, Mori S, et al. p38 MAPK mediated fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts. Hepatology, 2003,38:879-889.
  • 5Liu C, Gaca MD, Swenson ES. Smads 2 and 3 are differentially activated by transforming growth factor-β (TGF-β) in quiescent and activated hepatic stellate cells. J Biol Chem, 2003,278:11721-11728.
  • 6Pinzani M. PDGF and signal transduction in hepatic stellate cells. Front Biosci, 2002, 7:720-1726.
  • 7Maeda N, Kawada N, Seki S, et al. Stimulation of proliferation of rat hepatic stellate cells by galectin-1 and galectin-3 through different intracellular signaling pathways. J. Biol. Chem., 2003,278: 18938-18944.
  • 8Borkham-Kamphorst E, Stoll D, Gressner AM, et al. Inhibitory effect of soluble PDGF-beta receptor in culture-activated hepatic stellate cells. Biochem Biophys Res Commun, 2004,317:451-462.
  • 9Cao Q, Mak KM, Ren C, et al. Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells: respective roles of the JAK/STAT and JAK-mediated H2O2-dependant MAPK pathways. J Biol Chem, 2004,279:4292-4304.
  • 10Scharf JG, Dombrowski F, Novosyadlyy R, et al. Insulin-like growth factor (IGF)-binding protein-1 is highly induced during acute carbon tetrachloride liver injury and potentiates the IGF-I-stimulated activation of rat hepatic stellate cells. Endocrinology,2004,145:3463-3472.

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