碱性成纤维细胞生长因子在颗粒脂肪移植后血运重建过程的作用

The function of basic fibroblastic growth factor on revascularization of pearl fat graft transplantation

目的 探讨碱性成纤维细胞生长因子对颗粒脂肪移植存活的作用。方法 在颗粒脂肪移植的实验动物模型应用碱性成纤维细胞生长因子 ,通过对不同时期实验侧和对照侧移植体血管密度的定量研究 ,观察血管生长情况。结果 微血管显影清晰。对照侧和实验侧术后各期血管密度逐渐增高。对照侧于 2 8d达最高 ,实验侧于 14d达最高 ,以后稍有下降。每组实验侧均高于对照侧。

Objective To investigate the function of basic fibroblastic growth factor on the survival of fat transplantation. Methods Basic fibroblastic growth factor was used in pearl fat graft transplantation on experimental animal models. Microvessels densities both on experimental sides and control sides were quantitatively researched in various periods. The growth course of vessels was observed. Results Microvessels can be observed clearly. The Microvessels densities both on experimental sides and control sides raised gradually. The density reached highest in 14 days on experimental side and in 28 days on control side, and fell down slightly later. The densities on every experimental sides were higher than that on control sides. Conclusions Basic fibroblastic growth factor can effectually accelerate the growth of blood vessels in pearl fat graft.;