236株铜绿假单胞菌感染的临床分析

Pseudomonas aeruginosa from Nosocomial Infections: A Clinical Analysis of 236 Strains

目的调查铜绿假单胞菌感染的临床状况,探讨其发生原因及预防措施。方法 对45例铜绿假单胞菌感 染病例的各类临床标本得到的236分离株进行统计分析。结果 危重、老年和意外伤抢救患者是铜绿假单胞菌 的易感人群;住院周期长、侵入性技术的应用、交叉感染和细菌多重耐药是感染的主要因素;重症监护病房、老年 病房是高发科室;感染部位以呼吸道为主,术后伤口次之。结论缩短住院日,加强重点部位、重点人群的监测和 感染管理是预防铜绿假单胞菌医院感染的有效措施。

OBJECTIVE To investigate clinical infection situation of Pseudomonas aeruginosa (PAE) and to try to find out the causes and the preventive measures of the infections. METHODS Statistical analysis of 236 strains of PAE isolated from various clinical specimens of 45 cases of nosocomial infections was done. RESULTS The most susceptible crowd of PAE infections was those patients in critical conditions, senile patients and patients with major accidental wounds. The main correlative factors of the infections included in long-term hospitalization, application of aggressive procedures, cross infections and multi-drug resistant bacteria. The highest incidence rate of the infections was seen in those divisions including intensive care units (ICU) and geriatric units. The main infection sites were respiratory tracts, followed by post-surgery wounds. CONCLUSIONS To shorten patient hospitalization, to augment monitoring of key units and susceptible crowd, and to avoid cross infections are recommended to use to prevent the PAE infections.