纤维结合蛋白对牙周韧带细胞中肌动蛋白微丝的调节作用

The regulating effect of fibronectin on actin in periodontal ligament cells.

采用免疫组织化学、透射电镜方法观察了纤维结合蛋白(FN)对体外培养的牙周韧带(PDL)细胞中肌动蛋白微丝的调节作用.结果显示:FN组PDL细胞中肌动蛋白含量明显较对照组增高(P<0.01).且超微结构可见该细胞中微丝成份丰富.排列密集.提示FN可促进PDL细胞中微丝的聚合,并讨论了微丝聚合度增加与促进牙周新附着的关系.

By immunohistochemical methods and TEM, we observed the change of actin in periodontal ligament cells (PDL桟) when fibroncctin(FN) was applied. The results showed that exogenous FN could promote actin synthesis in PDL桟 significance (P<0.01). This finding was helpful for us to recognize the mechanism of periodontal tissue rcgencra-