摘要
目的探讨乌司他丁在腹部大手术围手术期应用对患者肝肾功能的影响。方法86例病人随机分为对照组(45例)和治疗组(41例)。治疗组在术前第1天、术后第1天到第5天静脉滴注乌司他丁20万单位,而对照组仅作常规治疗,分别检测术前与术后第1、3、5、7天患者肝肾功能指标,进行统计学处理。结果腹部大手术对患者肝肾功能有损伤作用,治疗组术后肝肾功能指标明显好于对照组,具有统计学差异(P<0.05)。结论乌司他丁对腹部大手术的患者能较好地保护其肝肾功能,减少机体对手术创伤的侵袭。
Objective To investigate the application of ulinastatin in the effects of hepatorenal function during perioperative period of abdominal major operations.Methods 86 patients received abdominal major operations were randomly divided into control group(45 cases)and therapeutic group(41 cases).The ulinastatin of 0.2 million unit was used by I.v.drip/per day in the terapeutic group from the day before operation and postoperative first to fifth day.The control group was only as a routine treatment.The hepatorenal function indexes were determined in both groups during hefore operation and post operative 1,3,5,7 day respectively.Results Damage of hepatorenal function might be caused by adbominal major operations.Postoperative indexes of hepatorenal function of therapeutic group was obviously better than that the control group.It had a significant difference in statistieally(P < 0.05) . Conclusion The ulinastatin can protect the hepatorenal function and reduce the operative traumatic reaction for patients with abdominal major operations.
出处
《岭南现代临床外科》
2005年第1期30-31,38,共3页
Lingnan Modern Clinics in Surgery
