米非司酮配伍米索前列醇治疗稽留流产486例分析

Analysis of Mifepristone and Misprostol in curing 486 missed abortion patients

目的 :探讨米非司酮配伍米索前列醇治疗稽留流产的可行性及安全性。方法 :对经 B超诊断稽留流产的 486例患者 ,口服米非司酮及米索前列醇进行药物流产 ,随机选择同期早、中孕行药物流产 60 0例做对照 ,观察其疗效、排胎时间、阴道出血量及副作用。结果 :研究组完全流产 3 4 1例 ,不全流产 12 3例 ,无效 2 2例 ,总有效率 95.48% ,平均排胎时间 6.2 3± 4.2 6h,出血量 3 5.6± 15.2 6ml,无严重并发症 ,与同期早孕药物流产对照组无显著差异。结论

Objective:To eval uate the feasibility and security of Mifepristone and Misoprostol in curing miss ed abortion Methods:Select 486 patients diagnosed as missed abortion with ultrasound ,taking Mifepristone and Misoprostol to abort,and choose 600 pat ients in random as a match group while in the early and middle pregnancy in the same period Observe the effect,abortion time,viginal bleeding dose and side eff ects Results:In the studying group 341 patients complete aborti on,123 patients incomplete abortion,22 patients invalid,the whole utility rate w as 95 48%,the average abortion time was 6 23±4 26 hrs Bleeding dose was 35 60±15 26 ml,without serious complications There was no significant differen ce between two groups Conclusion:Using Mifepristone and M isoprostol in curing missed abortion is as safe as medical abortion in pregnanc y