48例多血质貌新生儿高血粘滞度临床分析

Clinical analysis about 48 cases of sanguineous neonates with blood-hyperviscos ity

目的 :探讨多血质貌新生儿高血粘滞度出现的时间、临床表现及治疗。方法 :对 2 0 0 2年 3月～ 2 0 0 3年 6月收入儿科日龄 3～ 6d,平均生理性体重下降 8.18% ,有临床症状的 48例多血质貌新生儿 (排除有慢性缺氧史患儿 ) ,行微量血气分析 ,血色素 (Hb) ,血球压积 (Hct)和血液流变学检验。经治疗后于 72～ 84h复查。结果 :48例患儿 Hb>2 0 0 g/ L ,Hct>0 .6,血液流变学全血粘度各值明显高于参考值。治疗前后对照 Hb、 Hct差异有高度显著性 (P<0 .0 0 1) ,血液流变学差异有高度显著性(P<0 .0 0 1) ,无 1例出现低血容量性贫血。结论 :多血质貌新生儿虽然 Hb、 Hct值不符合红细胞增多症的诊断标准 ,但全血粘滞度明显增高 ,其增高程度与生理性体重降低有关 。

Objective: To explore the time when the blood-hyperviscosity exists, c linical behave and treatment of the neonates with sanguineous appearance Methods: Hb, HCT and Blood-rheology for 48 neonates with sanguineous appe arance were determined These were redetermined after 72~84 hours of treament Results: The value of Hb, HCT and Blood- rheology of 48 cases were obviously higher than the normal value Ther e w as significant difference between the values of Hb,HCT and Blood-rheology befor e treatment and those after treatment (P<0 001) Only one case enc ountered hypovolaemia Conclusion: Although the Hb, HCT level of the neonates wit h sanguineous appearance are not up to the diagnosis standard of polycythemia, b ut their blood-viscosity obviously heightened The heightening degree is relat ive to physiological weight-decrease It should be actively treated