泰能的体外抗菌活性试验

The Antibacterial Activity of Tienam in Vitro

目的:考察泰能(亚胺培南/西司他丁)的体外抗菌活性。方法:采用琼脂二倍稀释法测定泰能和其他3种药物对136株临床分离菌的体外抗菌活性。结果:泰能对金黄色葡萄球菌、绿脓杆菌、大肠杆菌、肺炎克雷伯氏菌、表皮葡萄球菌、β-溶血性链球菌、阴沟肠杆菌和微球菌的抗菌活性优于海舒必、他唑西林和头孢他啶,对肺炎球菌的抗菌活性较海舒必和头孢他啶弱。结论:泰能对本试验中所有的受试菌有较强的抗菌活性。

Objective:To investigate the antibacterial activities of Tienam in vitro.Methods:The antibacterial activities of Tie nam and other3drugs against 136clinical isolate in vitro were determined with double broth dilution method.Results:The activity of Tienam against S.aureus,P.eruginosa,E.coli,K.peneumoniae,S.epidermidis,β-Hemolytic streptococcus,E.cloacae and Micrococcus was superior to Sulbactam sodium/Cefopexazone sodium,Tazocin and Fortum.The activity of T ienam against S.pneumoniae was infe rior to Sulbactam sodium/Cefopexazone sodium and Fortum.Conclusion:Tienam has a good activity profile ag ainst all strains involved in this study.