江苏省人群中甲1型流感抗体的血清学监测

Serological surveillance on influenza H1 antibody of population in Jiangsu province

目的 了解江苏省人群中甲 1型流感抗体水平及其流行病学特征 ,为流感的预防提供科学依据。方法 利用微量半加敏血凝抑制试验方法检测江苏省不同地区 (南京、徐州、无锡 )、不同自然人群〔养禽场农工、养猪场农工、靠近 (<5 0 0m)及远离 (>10 0 0m)养殖场居民〕中甲 1型流感抗体水平 ,结合流行病学资料进行统计分析。结果 江苏省人群甲 1型流感抗体阳性率为 32 96 % ,护体保护率为 7 36 % ,抗体GMT为 1∶7 96。甲 1型抗体水平存在地区、年龄差异 ,徐州地区抗体水平高于其它两地区 ,2 5岁以下年龄组抗体水平高于其他年龄组 ,其中 15岁以下年龄组抗体阳性率和抗体GMT最高。甲 1型抗体水平 2 0 0 0年和 2 0 0 1年比较无显著性差异。结论 江苏省人群中甲 1型流感抗体水平偏低 ,全省仍存在局部爆发或流行的潜在危险。

Objective To understand the antibody levels of influenza H1 among the people in Jiangsu province,to describe the distribution characteristics of influenza H1NA,in order to acquire the basic seroepidemiolgocial material of influenza H1NA.Methods The antibody of influenza H1 was measured by the hemagglutination inhibition test.The antibody come from natural populations (e.g.farmers who breed fowls or pigs,residents who live around farm or a little far)living in different areas(Xuzhou,Nanjing,Wuxi) of Jiangsu province.Combining with the epidemiological data,the results are analyzed by statistical χ 2 test methods.Results The positive rate of antibody of influenza (H1NA) viruses was 32 96%,and GMT was 1∶7 96 among the population in Jiangsu province.The antibody levels of subtype H1 were different in areas and ages.The antibody levels among the human populations in Xuzhou were higher than that in the other areas.The antibody positive rates and GMT in other age groups were lower than the age group <25 years,especially in the age group <15years.The antibody levels of subtype H1 were found no difference at the aspects of occupation and years (between 2000 and 2001).Conclusion The antibody levels of subtype H1 were lower among the people in Jiangsu province.The risk to break out is still in existence.