山楂提取物对人体血脂影响的研究

Study on effect of hawthorn fruit extraction on human blood lipids

目的 观察山楂提取物对于高脂血症的治疗效果。方法 采用自身对照的方法。 4 5名受试者每天食用山楂提取物样品 3 6 g(浓度 10 % ) ,食用时间为 3个月。食用前和食用期间分别进行连续 3d膳食调查 ,确保受试者在食用期间不改变饮食习惯。并于食用于前、食用后每个月分别进行血脂生化指标测定 ,分别为高密度脂蛋白 胆固醇 (HDL C)、总胆固醇 (TC)和甘油三酯 (TG) ,低密度脂蛋白 胆固醇 (LDL C)由公式计算得出。结果 山楂提取物能明显降低血清TC、TG和LDL C浓度 ,对HDL C作用不明显。结论 山楂提取物对高脂血症人群具有良好的调节血脂作用。

Objective To observe the effect of hawthorn fruit extraction on the blood lipids of the hy perlipidemia.Methods Atuo-control method was used.45 volunteers took the hawthorn fruit extraction contained samples 3.6?g(10%) daily for 3 m onths .The 3-day diet record was taken before and during the test to ensure their die tary habits were maintaned.Their blood was sampled before the test and at the en d of ev ery month for serum lipids analysis.Total cholesterol(TC),triglyceride(TG)and hi gh-density lipoprotein HDL levels were determined.Low-density lipoprotein(LDL) was calculated by a formula.Results The hawthorn fruit extraction significantly decre ased the levels of serum TG(>15%),TC(>10%)and LDL-C(P<0.05),but it had n o significant effect on HDL-C.Conclusion The hawtorn fruit extraction had significant b enefit on the blood lipids of the hyperlipidemia.