嚼碎后舌下含服地尔硫卓即时降压效应的观察

The Instant Reactions on Blood Pressure After Subtongue Diltiazem

本文观察了24例原发性高血压病人嚼碎后舌下含服地尔硫(艹卓)后,血压的即时变化。发现用药30min后,平均动脉收缩压由用药前25.28±2.74kPa降为22.39±2.81kPa,用药60min后降为20.42±2.17kPa(P<0.001),用药30、60min后,平均动脉舒张压由15.23±2.0kPa降为13.44±1.82kPa和12.48±1.74kPa(P<0.01)。该结果显示,地尔硫(艹卓)具有即时降压作用。

The instant variations of the blood pressure in 24 patients with essential hypertension were observed after subtongue diltiazem. The average systalic blood pressure (SBP) decreased from 25.28±2.74 kPa to 22.39±2.81 kPa in 30 minutes after subtongue diltiazem and the average SBP decreased from 22.39±2.81 kPa to 20.42±2.17 kPa in 60 minutes (P<0.001). After subtongue diltiazem in 30, 60 minutes, the diastalic blood pressure seperatively decreased from 15. 23±2. 20kPa to 13.44±1.82 kPa and 12. 48±1.74kPa (P<0.01). These results strongly suggest that diltiazem has the effect of the speedy decrease of blood pressure.