离子型造影剂不良反应的回顾性调查

The Retrostectice Investigation on the Side Effects of Ionic Contrast

对1992年1月至1993年11月北京红十字朝阳医院离子型造影剂泛影葡胺及An-giografin的不良反应发生率进行了统计.泛影葡胺1420例,发生不良反应36例,发生率为2.5%;Angiongrafin1174例,不良反应12例,发生率为1.0%.国内外大量调查研究资料表明,非离子型造影剂的不良反应显著低于离子型造影剂,但由于非离子型造影剂的售价明显高于离子型造影剂,考虑到效用-价格比的原则,提出合理使用造影剂的几点建议,以减少不良反应的发生.

The side effects of ionic contrast medium: meglucamine diatrizoate and angiografin, had been invested in our hospital from Janrary of 1992 to November of 1993. The results showed that 36 of 1420 cases (2. 5%) who used Meglucamine Diatrizoate had the side effects, but the percentage of side effect of Angiografin was only 1%(12 of 1174 cases). A lot of researches had suggested that the side effect of non-ionic contrast medium was obviously lower than that of ionic contrast medium. But the price of non-ionic contrast medium was much higher. Regarding to the principle of the ratio of effect to price, we give some suggestion on the available use of contrast medium to reduce the side effects.