摘要
在ＮａＯＨ底液中，双嘧达莫在汞电极上有一不可逆的线性扫描还原峰，ＥＰＣ＝—１．３９Ｖ（ｖｓ饱和Ａｇ／ＡｇＣｌ）。该峰具有明显的吸附性。当搅拌富集时间较长、双嘧达莫的浓度较小、扫描速度较快时，电极反应几乎完全为吸附态的双嘧达莫所控制。选相交流伏安等实验表明，吸附型体为双嘧达莫中性分子。测得该体系的电子转移数ｎ为４，不可逆吸附的αｎα值为１．７２。探讨了双嘧达莫的电极反应机理。
In a supporting electrolyte containing NaOH , an
irreversible reduction peak ofdipyridamole( DPD ) was found by
linear-sweep Voltammetry at Hg electrode. The peak shows apotentlaI
Of 1.39 V(us Ag/AgCl)and adsorptive characteristics.When the
concentration of DPDis sufficiently low ,the sweep rate sufficiently
rapid and the accumulation time sufficiently long , thepeak current
is almost totally contributed by the reduction of adsorbed DPD. The
experiments of phaseselective AC voltammetry indicate that the
adsorbed species is most probably neutral DPD molecule.The number of
electrons transferred per DPD molecule,n,is 4 and the value of ana of
the irreversibleadsorptive system of DPD is l.72.The mechanism of
electrochemical reduction of DPD at HgeIectrode was explored. The
optimized condition for measuring trace amount of DPD by
adsorptivestripping voItammetry was established.
出处
《药学学报》
CAS
CSCD
北大核心
1994年第11期856-861,共6页
Acta Pharmaceutica Sinica
基金
国家自然科学基金
关键词
双嘧达莫
电化学行为
吸附性质
Dipyridamole
Electrochemical behavior
Adsorptive properties
