肛疾舒洗剂质量标准研究

Study on Quality Standard of Ganggishulotion

目的:研究肛疾舒洗剂的质量标准,以控制该制剂质量.方法:采用TLC法分别对大黄、黄柏、徐长卿、樟脑等进行定性鉴定,用分光光度法测定该制剂中有效成分总蒽醌的含量.结果:TLC鉴别专属性强,含量测定以大黄素为对照品,浓度在2.51～12.57μg·ml-1的范围内,线性关系良好,r=0.999 9;平均回收率为96.94%(n=5),RSD为0.86%.结论:本质量标准可有效控制该制剂的质量且方法简单,准确,实用.

Objective: To study a quality standard of Ganggishu lotion to control its quality. Method: TLC were used to identify Rhubarb, Corktree Bark, Cynanchum Paniculatum, and Camphor. Spectrophotometry was used to determine the content of total anthraquinones in Rhubarb. Result: The TLC have strong specificities.The linearity of emodin was obtained within the range of 2.5- 12.57 μg·ml -1, r= 0.999 9. The arerage recovery was 96.94%.RSD= 0.86%. Conclusion: This quality scandard was capable of effectively controlling the quality of Ganggishu.