手性相转移催化剂的合成和不对称诱导效应Ⅳ——手性双季铵盐

Synthesis and asymmetric induction effect of chiral phase transfer catalyst Ⅳ.Chiral diquaternary ammonium salts

以 (- ) 苯丙氨酸、(+) 樟脑酸和 (- ) 氯霉素为原料 ,合成了 3种手性双季铵相转移催化剂 ,它们在α- 羟基苯乙酸的合成中显示良好的催化作用和一定的不对称诱导效应。

Three chiral diquaternary ammonium salts were synthet is ed by using L-(-)-phenylalanine,(+)-camphoric acid and (-)-chloamphenico l.They displayed excellent phase transfer catalytic property and certain asymm etric induction effect in synthesis of amygdalinic acid.