摘要
目的为了解江门市人群乙型肝炎病毒(HBV)感染模式与丙型肝炎病毒(HCV)双重感染情况,进行血清病原学检测.方法选取774例HBV感染阳性血清,同时用ELISA方法作抗-HCV检测.结果对1998年7月～2003年12月间体检中检出的774例标志物阳性血清归类分析,发现有18种HBV感染模式,其中以HBsAg、HBeAb、HB-cAb和HBsAg、HBeAg、HBcAb为多见,阳性构成比分别为42.38%和29.97%.在HBV感染者中HCV感染的检出率为11.63%.不同HBV感染模式组别的抗-HCV阳性率差异有显著性意义(x2=24.38,P＜0.001).结论既往感染过HBV,不仅没有交叉免疫力,而且重叠感染HCV的危险性增加,应引起高度重视.
Objective To explore the pattern of HBV markers and distribution of coinfected with HBV and HCV among population. Methods Sera from 774 cases with positive HBV markers were de tected of HCV by ELISA. Results The results showed that 18 patterns were found.The p a ttern of positive HBsAg,HBeAb,HBcAb,(42.38)and the pattern of positive HBsAg,HB c ag,HBcAb(29.97%) were more often seen.The difference of the positive rate of a nt i-HCV among various patterns of HBV markers was significant(χ~2=24.38,P< 0.001). Conclusion Special attention be paid to the increase of risk of coinfection with HCV in patients previous infectied with HBV and without cro ss immunity.
出处
《中国热带医学》
CAS
2005年第2期370-371,共2页
China Tropical Medicine
